SB 431542 from Tocris Bioscience, a Bio-Techne Brand

Product Specs
ItemSB 431542
CompanyTocris Bioscience, a Bio-Techne Brand
Price Pricing Info Supplier Page View Supplier Product Page
Catalog Number1614/1
Quantity1 mg (also 10 mg, 50 mg)
Brand/TrademarkTocris, a Bio-Techne Brand
Purity0.99
Molecular Weight384.39
Molecule Name4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
FormulaC₂₂H₁₆N₄O₃
StorageStore at RT

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Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

Company Profile

Website: http://www.tocris.com

(1) Combined small-molecule treatment accelerates maturation of human pluripotent stem cell-derived neuronsNature biotechnologyJanuary 2, 2024Hergenreder E, Minotti AP, Zorina Y, Oberst P, Zhao Z, Munguba H, Calder EL, Baggiolini A, Walsh RM, Liston C, et al.

(2) An in vivo neuroimmune organoid model to study human microglia phenotypesCellMay 11, 2023Schafer ST, Mansour AA, Schlachetzki JCM, Pena M, Ghassemzadeh S, Mitchell L, Mar A, Quang D, Stumpf S, Ortiz IS, et al.

(3) An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cellsSTAR protocolsDecember 16, 2022Surendran H, Soundararajan L, Reddy K VB, Subramani J, Stoddard J, Reynaga R, Tschetter W, Ryals RC, Pal R.

(4) Enhanced cortical neural stem cell identity through short SMAD and WNT inhibition in human cerebral organoids facilitates emergence of outer radial glial cellsNature cell biologyJune 1, 2022Rosebrock D, Arora S, Mutukula N, Volkman R, Gralinska E, Balaskas A, Aragonés Hernández A, Buschow R, Brändl B, Müller FJ, et al.

(5) Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational UseCell stem cellFebruary 4, 2021Kim TW, Piao J, Koo SY, Kriks S, Chung SY, Betel D, Socci ND, Choi SJ, Zabierowski S, Dubose BN, et al.

(6) Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01Cell stem cellFebruary 4, 2021Piao J, Zabierowski S, Dubose BN, Hill EJ, Navare M, Claros N, Rosen S, Ramnarine K, Horn C, Fredrickson C, et al.

(7) A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and OrganoidsCell stem cellJuly 2, 2020Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffré F, et al.

(8) Bioelectrical domain walls in homogeneous tissuesNature physicsMarch 1, 2020McNamara HM, Salegame R, Al Tanoury Z, Xu H, Begum S, Ortiz G, Pourquie O, Cohen AE.serum replacement (Invitrogen, Cat. # 10828028), 10 μM of the TGFβ inhibitor SB431542 (Tocris, Cat. # 1614), 1 μM Chiron (Tocris, Cat. # 4423), 0.2% Pen/Strep (Life Technologies, Cat. # 15140122) and 1x ITS (Life Technologies

(9) The Interaction Between Nodal, Hypoxia-Inducible Factor 1 Alpha, and Thrombospondin 1 Promotes Luteolysis in Equine Corpus LuteumFront Endocrinol (Lausanne)October 1, 2019Edyta Walewska, Karolina Wołodko, Dariusz Skarzynski, Graça Ferreira-Dias, António GalvãoVolume 10 | Article 667 Walewska et al. Nodal, HIF1α, and TSP1 in Luteolysis in Mares (SB) (10 µM, 1614/1, R&D Systems); (iii) PGF2α (10−7 M); and (iv) simultaneously SB (10 µM) and PGF2α (10−7 M). Both PGF2α

(10) Maternal pluripotency factors initiate extensive chromatin remodelling to predefine first response to inductive signalsNature communicationsSeptember 19, 2019Gentsch GE, Spruce T, Owens NDL, Smith JC.

(11) An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neuronsFluids and barriers of the CNSAugust 7, 2019Canfield SG, Stebbins MJ, Faubion MG, Gastfriend BD, Palecek SP, Shusta EV.

(12) Supporting data on in vitro cardioprotective and proliferative paracrine effects by the human amniotic fluid stem cell secretomeData in briefAugust 1, 2019Balbi C, Lodder K, Costa A, Moimas S, Moccia F, van Herwaarden T, Rosti V, Campagnoli F, Palmeri A, De Biasio P, et al.

(13) Low-density lipoprotein receptor-deficient hepatocytes differentiated from induced pluripotent stem cells allow familial hypercholesterolemia modeling, CRISPR/Cas-mediated genetic correction, and productive hepatitis C virus infectionStem cell research & therapyJuly 29, 2019Caron J, Pène V, Tolosa L, Villaret M, Luce E, Fourrier A, Heslan JM, Saheb S, Bruckert E, Gómez-Lechón MJ, et al.

(14) Transforming growth factor-beta renders ageing microglia inhibitory to oligodendrocyte generation by CNS progenitorsGliaJuly 1, 2019Baror R, Neumann B, Segel M, Chalut KJ, Fancy SPJ, Schafer DP, Franklin RJM.

(15) Neurons Derived from Human Induced Pluripotent Stem Cells Integrate into Rat Brain Circuits and Maintain Both Excitatory and Inhibitory Synaptic ActivitieseNeuroJuly 1, 2019Yin X, Xu JC, Cho GS, Kwon C, Dawson TM, Dawson VL.

(16) The Spatiotemporal Control of Zygotic Genome ActivationiScienceJune 28, 2019Gentsch GE, Owens NDL, Smith JC.

(17) Neuropathy-causing mutations in HSPB1 impair autophagy by disturbing the formation of SQSTM1/p62 bodiesAutophagyJune 1, 2019Haidar M, Asselbergh B, Adriaenssens E, De Winter V, Timmermans JP, Auer-Grumbach M, Juneja M, Timmerman V.

(18) Efficient Generation of Trunk Neural Crest and Sympathetic Neurons from Human Pluripotent Stem Cells Via a Neuromesodermal Axial Progenitor IntermediateCurrent protocols in stem cell biologyJune 1, 2019Frith TJR, Tsakiridis A.

(19) Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human EmbryoStem cell reportsMay 14, 2019Easterbrook J, Rybtsov S, Gordon-Keylock S, Ivanovs A, Taoudi S, Anderson RA, Medvinsky A.

(20) Long-term functional maintenance of primary human hepatocytes in vitroScience (New York, N.Y.)April 26, 2019Xiang C, Du Y, Meng G, Soon Yi L, Sun S, Song N, Zhang X, Xiao Y, Wang J, Yi Z, et al.

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(1)

10/4/2016Inhibitor Of The Transforming Growth Factor-ß Sadaf AtarodThe aim of this project was to inhibit the TGF-beta signaling pathway during the directed differentiation protocol. The product has proven stability & has been used by various labs.

SB 431542

SB 431542

SB 431542 from Tocris Bioscience, a Bio-Techne Brand

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Tocris Bioscience, a Bio-Techne Brand

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SB 431542 from Tocris Bioscience, a Bio-Techne Brand

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